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	Roy D. Dar 2001- 2004 B.Sc. Physics and Mathematics , Hebrew University of Jerusalem, Israel (HUJI) May-August 2004 Student Research Assistant in Prof. Dan Davidov’s Experimental Condensed Matter Group, HUJI. Topic: Scanning ferromagnetic resonance microscopy and resonant heating of magnetite nanoparticles (with F. Sakran, Ph.D.) Jan-Sept 2005 Science Undergraduate Laboratory Internship through the DOE-Office of Science with the Molecular-Scale Engineering and Nanoscale Technologies (MENT) Research Group at the Oak Ridge National Laboratory (ORNL). Topic: Experimentation and Modeling of Stochastic Processes in Bacterial Cells. 2006 – present Graduate Research Assistant in the “Emergent Properties” theme at ORNL’s Center for Nanophase Materials Sciences under the direction of Dr. Michael Simpson. Concentration: Biological physics. Topic: Organizational principles of complex genetic systems. Publications “Noise in Biological Circuits,” M. L. Simpson, C. D. Cox, M. S. Allen, J. M. McCollum, R. D. Dar, D. K. Karig, and J. F. Cooke, John Wiley & Sons, Inc. WIREs Nanomed Nanobiotechnol 1 214-225 (2009). “Transient-mediated fate determination in a transcriptional circuit of HIV,” L. S. Weinberger*, R. D. Dar* & M. L. Simpson. Nature Genetics 40, 466 - 470 (2008) * -- Equal Contribution. link (See news and views Highlight: Nachman and Ramanathan, Nature Genetics 40, 382 - 383 (2008) ) “Using noise to probe and characterize gene circuits,” C. D. Cox, McCollum J.M., Allen M.S., Dar R.D., and M.L. Simpson, Proc. Nat. Acad. Sci. USA, 105(31), 10809-10814. (2008). link "Gene Network Shaping of Inherent Noise Spectra," D. W. Austin, M. S. Allen, J. M. McCollum, R. D. Dar, J. R. Wilgus, G. S. Sayler, N. F. Samatova, C. D. Cox, and M. L. Simpson, Nature 439, 608-611 (2006). link “Frequency domain analysis of noise in simple gene circuits,” C. D. Cox, J. M. McCollum, D. W. Austin, M. S. Allen, R. D. Dar, and M. L. Simpson, Chaos 16, 026102 (2006). link “Estimation of spectral properties and kinetic parameters from stochastic measurements of reporter gene activity in single cells,” C. D. Cox, J. M. McCollum, D. W. Austin, R. D. Dar, M. S. Allen, N. F. Samatova, and M. L. Simpson. 2005. Foundations of Systems Biology in Engineering; Santa Barbara, CA.357-360 (2005). Workshops and Conferences 2006 CNMS User Meeting, June 14-15 2006, Oak Ridge – Tennessee link (poster in link) Quantitative Approaches to Gene Regulatory Systems, July 9-21 2006, University of California – San Diego poster Downloadable CV CNMS 2009 Staff Bio Life at ORNL/UT Travel Photos Selected Drawings Random Quotes1 I have an insatiable love for life and learning bringing much balance to my life. To get a “slice of life” of my backpacking adventures see the following newspaper article which brought some closure to my trip: link I am ever thankful for the great people, resources, and opportunities made available to me in my life.

Figure from Austin et al, Nature (2006)

Representative fluorescent image from Nat Gen (2008)

Contact Information:

Work Phone: 865-574-6900
Email: darr@ornl.gov or darr@utk.edu
Oak Ridge National Laboratory
P.O. Box 2008
Building 8610, MS 6493
Oak Ridge, TN 37831-6493

Fall at the

		Cox et al, PNAS (2008) Fig. 1. Noise regulatory vector and its application in the analysis of gene circuits. (A) The noise regulatory vector for an uncharacterized gene circuit is determined by comparison of its experimental noise structure to the noise structure of an assumed model. The vector points toward a family of gene circuits that includes the true gene circuit, and away from inappropriate models.
Fall colors of East Tennessee