Protein Databases
(Assignment 9)

Protein Databases
Provided Information
The PIR, in collaboration with MIPS and JIPID, produces and distributes the PIR-International Protein Sequence Database (PSD), the most comprehensive and expertly annotated protein sequence database in the public domain.
- Protein function
- Domains structure
- Post-translational modifications
- Variants
- etc.
The UniProt/TrEMBL sequence database contains the translations of all coding sequences (CDS) present in the DDBJ/EMBL/GenBank Nucleotide Sequence Database and also protein sequences extracted from the literature or submitted to UniProt/Swiss-Prot, which are not yet integrated into UniProt/Swiss-Prot.
- Multiple alignments
- Protein domain architectures
- Species distribution
- Links to other databases
- Known protein structures

- Protein family
- Protein domains

- The structural and evolutionary relationships between all proteins whose structure is known
CATH is a novel hierarchical classification of protein domain structures, which clusters proteins at four major levels, Class(C), Architecture(A), Topology(T) and Homologous superfamily (H).


Searching CD14 domains using Pfam:
CD14 protein sequences

 


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