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The University of Tennessee

The Chemical & Biomolecular Engineering Department

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Dr. Eric T. Boder

Career Development Associate Professor
Ph.D., Illinois: Molecular biotechnology and bioengineering, protein engineering and directed evolution.

Brief Bio

Dr. Boder received his B.S. degree Summa Cum Laude in Chemical Engineering from Washington University in 1993 and earned M.S. and Ph.D. degrees in Chemical Engineering from the University of Illinois in 1996 and 1999, respectively.  Dr. Boder's thesis research focused on molecular engineering of single-chain antibodies by yeast display and directed evolution.  Following a short postdoc studying T cell immunology at National Jewish Medical and Research Center in Denver, CO, Dr. Boder joined the faculty in Chemical and Biomolecular Engineering at the University of Pennsylvania in 2000.  In 2007, Dr. Boder joined the faculty at UT-Knoxville, where his research program focuses on protein engineering and applied molecular biology.

Research Areas

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Biomolecular engineering applications in immune function

Viral membrane fusion proteins

Molecular switching and cell adhesion proteins

Protein immobilizing and modifying enzymes

Selected Awards and Honors

2003 National Science Foundation CAREER Award
2002 NAE Frontiers of Engineering Invitee

Professional Activities

» American Institute of Chemical Engineers
» Society for Biological Engineering
» The Protein Society
» American Chemical Society

Selected Publications

L.R. Pepper, Y.K. Cho, E.T. Boder, and E.V. Shusta:  "A decade of yeast surface display technology:  Where are we now?"  Comb. Chem. High Throughput Screen., 11:127-34 (2008).

R. Parthasarathy, S. Subramanian, and E.T. Boder:  "Sortase A as a novel molecular “stapler” for sequence-specific protein conjugation." Bioconj. Chem., 18:469-476 (2007).

J.H. Lee, M. Goulian, and E.T. Boder:  "Autocatalytic Activation of Influenza Hemagglutinin."  J. Mol. Biol., 364:275-282 (2006).

L.R. Pepper, D.A. Hammer, and E.T. Boder: "Rolling Adhesion of αL I Domain Mutants Decorrelated from Binding Affinity."  J. Mol. Biol., 360:37-44 (2006).

S. Park, Y. Xu, X.F. Stowell, F. Gai, J.G. Saven, and E.T. Boder:  "Limitations of yeast surface display in engineering proteins of high thermostability."  Prot. Eng. Des. Sel., 19:211-217 (2006).


Selected Patents

U.S. Patent 6,300,065 (2000):  Yeast cell surface display of proteins and uses thereof


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Contact Dr. Boder

427B Dougherty Engineering Bldg.
Department of Chemical and Biomolecular Engineering
University of Tennessee
Knoxville, TN 37996-2200
Tel: (865) 974-6362


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